Douglas A. Roth, M.D., F.A.C.S.
 
Plastic & Reconstructive Surgery

  EDUCATION:

B.S.  Chemistry,  1986
Massachusetts Institute of Technology, Cambridge,  Massachusetts
M.D.  1990
New York University School of Medicine, New York,  New York

TRAINING:

Anatomy Fellow   Summer, 1987
NYU School of Medicine - Supervised by Dr. Bruce Bogart

Volunteer work as Surgical Resident: May - June, 1990
Nigerian Christian Hospital: Nigeria, West Africa - Supervised by Dr. Maurice Hood

General Surgery Residency Program  1990 - 1996
Department of Surgery, New York University Medical Center

  • Internship:  1990-1991

  • Residency:           
     - Junior Resident: 1991-1992
     - Assistant Chief Resident: 1992-1993
     - Research Year 1993-1994
     - Junior Chief Resident: 1994-1995
     - Chief Resident: 1995-1996
     - Executive Chief Resident: 11/95-1/96

Plastic Surgery Residency Program  1996 – 1998
Institute of Reconstructive Plastic Surgery, New York University Medical Center

  • Executive Chief Resident   1997 - 1998

Fellowship in Microvascular Surgery 1998 – 1999
Institute of Reconstructive Plastic Surgery
New York University Medical Center / Bellevue Hospital

ACADEMIC
APPOINTMENTS
Assistant Clinical Professor, Plastic Surgery
Mount Sinai School of Medicine, New York, NY

BOARD CERTIFICATION

American Board of Surgery - December 1997
American Board of Plastic Surgery - September 2000

HOSPITAL PRIVILEGES

Northern Westchester Hospital Center
400 Main Street, Mount Kisco, N.Y.  10549
Full Staff Privileges: Plastic & Reconstructive Surgery

Faculty of Institute of Aesthetic Surgery & Medicine, Director of Medical Education

Manhattan Eye, Ear & Throat Hospital
210 East 64th Street, New York, N.Y.  10021

PROFESSIONAL ORGANIZATIONS

American College of Surgeons -  Fellow
American Society of Plastic Surgeons – Active Member          
New York Regional Plastic Surgery Society
Member, Board of Directors, Mount Kisco Medical Group
Quality Assurance Committee, Northern Westchester Hospital

  RESEARCH EXPERIENCE

1981 - National Science Foundation Summer Research Program, Flavenoid Biochemistry Laboratory, Dr. Thomas Mabry, University of Texas at Austin, Austin, TX

1983 - 1986  Undergraduate Research Program. Dr. Paul M. Newberne,vDepartment of Applied Biology, Massachusetts Institute of Technology, Cambridge, Mass.

1986 - 1988  Clinical and research work with Dr. Jesse B. Jupiter, Department of Orthopedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.

1993 - 1994  Craniofacial Research Fellow under the direction of Dr. Joseph G. McCarthy, Institute of Reconstructive Plastic Surgery, New York University Medical Center,  New York, N.Y.

1998 - 1999 Microsurgery Research, Microsurgery Laboratory

Institute of Reconstructive Plastic Surgery, New York University Medical Center,  New York, N.Y

RESEARCH GRANTS

Plastic Surgery Educational Foundation Research Grant: $5000.00 for Bone Growth Factors in Craniosynostosis, April, 1994. 

American Society of Maxillofacial Surgeons Research Grant Award: $6500.00 for The Effects of Locally Applied Exogenous Growth Factors in an In Vivo Model of Cranial Suture Fusion, November 11, 1996.

AWARDS

Westinghouse National Science Talent Search, 1982: Honors Award   Identification and Ellucidation of Plant Flavenoid Compounds

Bausch And Lomb First Place Science Award, 1982: Long Beach High School, Long Beach, New York

Alpha Chi Sigma Award in Chemistry, May 1986: Massachusetts Institute of Technology

Tai Foundation Scholarship Award, 1990: New York University School of Medicine 

First Place Basic Science Award, June 20, 1994: The Analysis of  TGF-b1, β2, β3 and IGF-1 in Cranial Suture Fusion in Rats and Humans. Residents' Research Night; Institute of Reconstructive Plastic Surgery, New York University Medical Center.

Second Place Basic Science Award, March 4, 1997: The effects of exogenous application of IGF-I, IGF-II, and TGF-b2 to rat cranial sutures. New York Regional Plastic Surgery Society Resident’s night competition.

Nominated for James Barrett Brown Award for the most outstanding plastic surgery paper in Plastic and Reconstructive Surgery in 1997 (The analysis of transforming growth factor b-1, b-2, b-3, and insulin-like growth factor-1 in premature cranial suture fusion in humans.)

First Place Basic Science Award June 22, 1999: Gene Therapy with VEGF improves flap survival in the rat TRAM flap model. Residents' Research Night; Institute of Reconstructive Plastic Surgery, New York University Medical Center.

PRESENTATIONS

1.  Volumetric studies after distraction osteogenesis of the mandible, presented at the Workshop on Distraction of the Craniofacial Skeleton, Institute of Reconstructive Plastic Surgery, New York University Medical Center, March 18-19, 1994.

2.  Analysis of transforming growth factor-b1, b2, and b3 in cranial suture fusion  Poster Presentation, NIH Conference on TGF-b 's, Bethesda, MD, May 4-6, 1994.

3.  The role of transforming growth factor-b1 in rat cranial suture fusion.  Presented at the 39th Annual Meeting of the Plastic Surgery Research Council, Ann Arbor, MI, June 6, 1994.

4.  The role of TGF-b1 in rat cranial suture fusion. Presented at the 63rd Annual ASPRS/PSEF/ASMS Scientific Meeting, San Diego, CA September 26, 1994.

5.  TGF-b1, b2, b3, and IGF-1 localization in rat cranial suture development and fusion.  Presented in the Neurosurgery Section, Surgical Forum, 80th Annual Clinical Congress, Chicago, IL October 11, 1994.

6.  The analysis of TGF-b1, b2, b3, and IGF-1 in premature cranial suture fusion in humans.  Presented in the Plastic Surgery Section, Surgical Forum, 80th Annual Clinical Congress, Chicago, October 12, 1994.

7.  Quantitative volumetric assessment after distraction osteogenesis of the mandible.  Presented at Residents’ Night, The New York Regional Society for Plastic and Reconstructive Surgery, New York Academy of Medicine, New York, March 6, 1995. 

8.  Growth factors in human craniosynostosis.  DA Roth, MT Longaker, JG McCarthy, VKM Han, LI Gold.  Presented at the 52nd annual American Cleft Lip and Cleft Palate Meeting,  Tampa, Fla., April 26th, 1995.

9.  In vivo and in vitro cranial suture fusion in the mouse.  JP Bradley, JP Levine, JG McCarthy, DA Roth, MT Longaker, C Blewitt, TM Krummel. Presented at the 52nd annual American Cleft Lip and Cleft Palate Meeting,  Tampa, Fla., April 27th, 1995.

10.  The role of the dura in cranial suture fusion.  DA Roth, JP Levine, JP Bradley, JG McCarthy, HF McMullen, MT Longaker.  Presented at the 40th Annual Meeting of the Plastic Surgery Research Council, New York, N.Y., May 19th, 1995.

11.  Exogenous application of IGF-1, IGF-2 and TGFb-2 to rat cranial sutures.  Poster Presentation.  JP Bradley, JP Levine, DA Roth, DM Rosen, JG McCarthy, MT Longaker. 40th Annual Meeting of the Plastic Surgery Research Council, New York, N.Y., May 18-20, 1995.

12.  In vivo and in vitro cranial suture fusion in the mouse: a laboratory model.  Poster Presentation.  JP Levine, JP Bradley, C Blewett, TM Krummel, JG McCarthy, MT Longaker. 40th Annual Meeting of the Plastic Surgery Research Council, New York, N.Y., May 18-20, 1995.

13.  Distraction of the Human Mandible: A Cephalometric and 3-Dimensional CT Voumetric Analysis. DA Roth, AK Gosain, AE Turk, MA Stracher, DR Lefton, BH Grayson, JG McCarthy.  Presented at the 64th annual ASPRS/PSEF/ASMS Scientific Meeting,  Montreal, Canada, October 9th, 1995.

14.   The effects of exogenous application of IGF-I, IGF-II, and TGF-b2 to rat cranial sutures. Presented at Residents’ Night, The New York Regional Society for Plastic and Reconstructive Surgery, New York Academy of Medicine, New York, March 4, 1997.

15.  Key Textbooks in the Development of American Plastic Surgery: The First Half of the 20th Century. Roth DA, Rogers BO, McCarthy JG.  Presented at the American Association of Plastic Surgeons, May 19, 1998, Montreal, Canada.

16.   Gene Therapy with Vascular Endothelial Growth Factor improves survival in the rat TRAM Flap. Roth DA, Kalish E, Castello JR, Chang H, Shankar R, Usal H, Crystal RG, Rosengart TK, Kasabian AK. Presented at the 44th Annual Plastic Surgery Research Council, Pittsburgh, PA, May 22-25, 1999.

ABSTRACTS

1.   Newberne PM, Adams K, Roth DA, Tannenbaum SR: Early changes in gastric carcinogenesis: Toxicologist 4: Abstract #200, 1984.      

2.   Charnley G, Adams K, Roth DA, Newberne PM: Risk factors in gastric cancer: early markers. Toxicologist 5: Abstract #160, 1985.                      

3.   Roth DA,  Longaker MT, Breitbart AS, McCarthy JG, Gold LI:  The role of TGF-b1 in rat cranial suture fusion.  39th Annual Plastic Surgery Research Council Meeting, Ann Arbor, MI,  June, 1994.

4.   Roth DA, Longaker MT, Breitbert AS, McCarthy JG, Gold LI: The role of TGF-b1 in rat cranial suture fusion.  Plastic Surgical Forum Vol XVII, p. 39, 63rd Annual ASPRS/PSEF/ASMS Scientific Meeting, San Diego, CA, September, 1994

5.  Roth DA, Levine JP, Bradley JP, McCarthy JG, McMullen HF, Longaker MT: The role of the dura in cranial suture fusion.  40th Annual Plastic Surgery Research Council Meeting,  New York, N.Y.,  May 19th, 1995.

6.  Bradley JP, Levine JP, Roth DA, McCarthy JG, Longaker MT: The effect of cranial suture rotation on fusion in the rat. 40th Annual Plastic Surgery Research Council Meeting,  New York, N.Y.,  May 19th, 1995.

7.  Roth DA, Gosain AK, Turk AE, Grayson B, Lefton DR, Stracher MA, McCarthy JG: Distraction of the human mandible: A cephalometric and 3-dimensional CT volumetric analysis.  Plastic Surgical Forum Vol XVIII, 64th Annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

8. Bradley JP, Han VKM, Roth DA, Levine JP, McCarthy JG, Longaker MT: The biology of cranial suture fusion: Growth factor signaling activates osteoblasts to induce suture fusion. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

9.  Bradley JP, Levine JP, Roth DA, Blewett C, Krummel TM, McCarthy JG, Longaker MT: In vivo and in vitro posterior frontal cranial suture fusion in the mouse. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

10. Levine JP, Bradley JP, Roth DA, McCarthy JG, Longaker MT: Regional dura mater determines overlying cranial suture biology. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

11. Roth DA, Kalish E, Castello JR, Chang H, Shankar R, Usal H, Crystal RG, Rosengart TK, Kasabian AK. Gene Therapy with Vascular Endothelial Growth Factor improves survival in the rat TRAM Flap. Abstract 7A, p 92,  44th Annual Plastic Surgery Research Council, Pittsburgh, PA, May, 1999.

12.  Chao JJ, Castello JR, Roth DA, Kasabian AK. Ligament and tendon reconstruction using an acellular dermal matrix. Abstract 54A, p. 146. 44th Annual Plastic Surgery Research Council, Pittsburgh, PA, May, 1999.

  PUBLICATIONS

Newberne PM, Charnley G, Adams K, Cantor M, Roth DA, Supharkarn V, Fong L:  Gastric and esophageal carcinogenesis: models for the identification of risk and protective factors.  Food and Chemical Toxicology.1986;  24: 1111-1119.

2.  Newberne PM, Charnley G, Adams K, Cantor M, Suphakarn V, Roth DA, Schrager TF: Gastric carcinogenesis: a model for the identification of risk factors.  Cancer Letters.  1987; 38:149-163.

3.  Jupiter JB, Ruder J, Roth DA:  Computer-generated bone models in the planning of osteotomy of multidirectional distal radius malunions.  J. Hand. Surg. 1992; 17A:406-415.

4.   Roth DA, Longaker MT, Han VK, Breitbart AS, Gold LI, McCarthy JG:  The analysis of TGF-b1, b2, b3, and IGF-1 in premature cranial suture fusion in humans. Surgical Forum Vol XLV:734-736, 1994.

5.   Longaker MT, Roth DA, McMullen HF, Breitbart AS, Wisoff JH, Han VK, Gold LI, McCarthy JG: TGF-b1, b2, b3, and IGF-1 localization in rat cranial suture development and fusion. Surgical Forum Vol XLV:589-591, 1994.

6.   Han VKM, Bradley JP, Roth DA, Levine JP, McCarthy JG, Longaker MT Dura mater-suture paracrine signaling during cranial suture fusion: IGF-I, IGF-II in situ-hybridization and IGF-I, osteocalcin immunolocalization in human and rat cranial sutures. Surgical Forum Vol XLVI:706-708 1995.

7.  Roth DA, Gosain AK, Turk AE, Grayson B, Lefton DR, Stracher MA, McCarthy JG: Distraction of the human mandible: A cephalometric and 3-dimensional CT volumetric analysis.  Plastic Surgical Forum Vol XVIII, 64th Annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

8. Bradley JP, Han VKM, Roth DA, Levine JP, McCarthy JG, Longaker MT: The biology of cranial suture fusion: Growth factor signaling activates osteoblasts to induce suture fusion. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

9.  Bradley JP, Levine JP, Roth DA, Blewett C, Krummel TM, McCarthy JG, Longaker MT: In vivo and in vitro posterior frontal cranial suture fusion in the mouse. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

10.  Levine JP, Bradley JP, Roth DA, McCarthy JG, Longaker MT: Regional dura mater determines overlying cranial suture biology. Plastic Surgical Forum Vol XVIII,  64th annual ASPRS/PSEF/ASMS Scientific Meeting, Montreal, Canada, October, 1995.

11.  Roth DA, Bradley JP, Levine JP, McMullen HF, McCarthy JG, Longaker MT: Studies in cranial suture biology: Part II. Role of the dura in cranial suture fusion.  Plast Reconstr Surg  97:693-699, 1996

12.  Bradley JP, Levine JP, Roth DA, McCarthy JG, Longaker MT:  Studies in cranial suture biology: Part IV. Temporal sequence of posterior frontal cranial suture fusion in the mouse. Plast Reconstr Surg 98:1039-1045, 1996.

13.  Roth DA, Gold LI, Han VK, McCarthy JG, Wisoff JH, Longaker MT: The analysis of transforming growth factor b-1, b-2, b-3, and insulin-like growth factor-1 in premature cranial suture fusion in humans. Plast Reconstr Surg  99:300-309 ,1997.

14. Roth DA, Longaker MT, McCarthy JG, McMullen HF, Gold LI: Studies in cranial suture biology: Part I. Increased immunoreactivity of transforming growth factor b-1, b-2, and b-3 during rat cranial  suture fusion. J Bone Miner Res 12:206-215, 1997.

15. Roth DA, Gosain AK, Stracher MA, Lefton DR, Grayson B, McCarthy JG: A CT scan technique for quantitative volumetric assessment of the mandible after distraction osteogenesis. Plast Reconstr Surg 99:1237-1247,1997.

16.  Roth DA, Longaker MT, Zide BZ: Cheek surface reconstruction: Best choices according to zone.  Operative Tech in Plast Reconstruc Surg 5: 2-30, 1998.

17.  Bradley JP, Roth DA, Han VKM, Levine JP, McCarthy JG, Longaker MT:  Immunolocalization of IGF-1, IGF-2, and BMP-4 and in-situ hybridization of IGF-1 and IGF-2 in rat cranial suture fusion. Plastic and Reconstructive Surgery, 1998

18.  Malhotra S, Roth DA, Gouge TH, Hofstetter SR, Sidhu G, Newman E: Gangrene of Meckel’s Diverticulum secondary to axial torsion: a rare complication.  Journal of Gastroenterology, October 1998.

BOOK CHAPTERS

Roth D.A.  Thoracic And Abdominal Wall Reconstruction. In S.J. Aston, R.W. Beasley, and C.H. Thorne (Eds), Grabb and Smith’s Plastic Surgery, 5th Edition, Philadelphia, Lippincott-Raven, 1997.

Roth D.A., Mackool R.J., McCarthy J.G. Volumetric Assessment After Mandibular Distraction. In J.G. McCarthy (Ed), Distraction Of The Craniofacial Skeleton, New York, Springer-Verlag, 1998.